简介:
方雪梅,女,博士,教授(三级)。现任资源与土木工程学院院长,主要从事生态环境评价与保护有关的教学与科研工作。
履历:
1991-1995年就读于安徽师范大学,获理学学士学位;
2002-2005年就读于陕西师范大学,获理学硕士学位;
2007-2010年就读于中国科学院动物研究所,获理学博士学位;
2011-2013年于大连理工大学从事博士后科研工作。
1998年至今在宿州学院任教,获评安徽省教学名师、安徽省高校学科(专业)拔尖人才、“宿州青年科技奖”、宿州学院学术技术带头人后备人选。
教学科研经历:
主持完成国家自然科学基金委青年科学基金项目、中国博士后科学基金面上项目、安徽省自然科学基金面上项目、安徽省高校学科(专业)拔尖人才项目、安徽省教育厅自然科学研究项目、安徽省高校优秀青年人才基金项目等多项科研项目。主持完成省级重大教研项目、省级特色专业、省级产业学院等多项质量工程项目,获得省级教学成果一等奖2项,二等奖3项,三等奖3项;在国内外学术刊物上发表学术论文40余篇,其中SCI检索10余篇,主编教材1部。
近年来代表性成果:
1. Fang X, Zhang X, Li H. Oxidative stress and mitochondrial membrane potential are involved in the cytotoxicity of perfluorododecanoic acid to neurons. Toxicol Ind Health. 2020, 36(11):892-897.
2. Fang X, Wu C, Li H, Yuan W, Wang X. Elevation of intracellular calcium and oxidative stress is involved in perfluorononanoic acid-induced neurotoxicity. Toxicol Ind Health. 2018, 34(3):139-145.
3. Fang X, Gao G, Zhang X, Wang H. Perfluorononanoic acid disturbed the metabolism of lipid in the liver of streptozotocin-induced diabetic rats. Toxicol Mech Methods. 2015; 25(8):622-627.
4. Fang X, Zou S, Zhao Y, Cui R, Zhang W, Hu J, Dai J. Kupffer cells suppress perfluorononanoic acid-induced hepatic peroxisome proliferator-activated receptor α expression by releasing cytokines. Archives of toxicology. 2012, 86(10):1515-1525.
5. Fang X, Gao G, Xue H, Zhang X, Wang H. Exposure of perfluorononanoic acid suppresses the hepatic insulin signal pathway and increases serum glucose in rats. Toxicology. 2012, 294(2-3):109-115.
6. Fang X, Gao G, Xue H, Zhang X, Wang H. In Vitro and In Vivo Studies of the Toxic Effects of Perfluorononanoic Acid on Rat Hepatocytes and Kupffer Cells. Environmental Toxicology and Pharmacology, 2012, 34(2):484-494.
7. Fang X, Feng Y, Wang J, Dai J. Perfluorononanoic acid-induced apoptosis in rat spleen involves oxidative stress and the activation of caspase-independent death pathway. Toxicology. 2010, 267(1-3):54-59.
8. Fang X, Wei Y, Liu Y, Wang J, Dai J. The identification of apolipoprotein genes in rare minnow (Gobiocypris rarus) and their expression following perfluorooctanoic acid exposure. Comp Biochem Physiol C Toxicol Pharmacol. 2010, 151(1):152-159.